Oral presentation
5' untranslated region, Translation control, translation initiation, RNA binding proteins, CRISPRi, cancer, screening
Public Summary
Selective translational control allows cancer cells to fine-tune the protein dosage of key oncogenes, such as MYC, to adapt and survive. We have identified selective regulators of MYC translation in pancreatic cancer.
Presenter
Joanna Kovalski, PhD
Postdoc
Davide Ruggero, University of California, San Francisco