Computational Biology, Extrachromosomal DNA, DNA Sequencing, Next-generation sequencing, bioinformatics, cancer, HIV, mitochondria, mitochondrial DNA, William Wang, Nimit Jain, Karen Artiles
Public Summary
Extrachromosomal DNA (ecDNA) plays a significant role in many biological processes such as cancer and viral infection. We present the identification of various ecDNAs in HIV and mitochondria using a method based on strand bias and end capture.