Vincent and Stella Coates Professor of Microbiology and Immunology, UCSF
Michael T McManus PhD

Dr. McManus is the Stella Coates Endowed Chair Professor at the University of California San Francisco, in the Department of Microbiology and Immunology. He is the founder and Director of the W.M. Keck Center for Noncoding RNAs and the Director of the ViraCore at UCSF. He has a long-standing interest in gene regulation and technologies that surround perturbation of gene expression. Over the last 15 years his group has developed high-throughput approaches, harnessing small RNAs for the interrogation of gene function and the potential use in the intervention of human disease. He is an extremely active collaborator, sharing his technology with a wide range of nationally and internationally recognized experts and regularly secures research funding, largely from national granting institutions such as the NSF and NIH. Recent outstanding awards include the W.M. Keck Foundation, an NIH Transformative award, and the Helen C. and Robert J. Kleberg, Jr. Foundation. Currently he is the leader of several major NIH awards focusing on CRISPR therapies, transposable element biology, cancer target discovery and development, cancer persister cell biology, and illuminating druggable dark matter. Working in cell lines and mouse models, his academic research lab maintains a very diverse research program with students and postdocs and research technicians working in a variety of research areas related to systems and synthetic biology. His recent work includes developing new RNA based tools and approaches to untangle genomic complexity as related to development and disease.

Michael T McManus PhD