Alex Buckley
Graduate Student
Daniele Canzio, University of California, San Francisco
Pronouns: he/him
I am a graduate student in the neuroscience program at UCSF working in Dr. Daniele Canzio's lab. Our group studies clustered protocadherins--proteins that mediate neuronal self-recognition and avoidance--and how their expression is regulated in different cell types to support different wiring needs. My research in particular focuses on how the 3D genome organization of the protocadherin locus relates to protocadherin expression in single cells.
Before starting at UCSF, I worked at the Broad Institute in Dr. Evan Macosko's lab developing genomic tools to study brain connectivity and disease. Before that, as an undergraduate at Washington University in St. Louis, I joined Dr. Jordan McCall's lab to study mesoscale circuits involved in stress and anxiety. I have also interned at Denali Therapeutics, where I developed biomarkers for two Parkinson's disease therapeutics, and the Allen Institute for Brain Science, where I studied the spread of beta-amyloid plaques throughout the brain in different Alzheimer's disease mouse models.
I am interested in neural wiring specificity, chromatin biology, technology development in molecular biology, and leveraging RNA in different forms to learn about biology.
My Presentations
Topics of Interest
- Bay Area RNA Conference
- RNA Structure
- RNA Technologies
- Sequence Exploration
- Gene Regulation
- In Vivo Function
- Workshops, Sessions, and Socials
- Careers in Industry